Wednesday, 15 June 2011

Stimulated Hormone (Estrogen)



"Frieza"
(Follicle-stimulating hormone)




Estrogen -  the primary female sex hormone.


Steroidal Types of Estrogens
  • E1 - estrone - produced during menopause
  • E2 - estradiol - predominant form in nonpregnant females
  • E3 - estriol - primary estrogen of pregnancy
How to remember:
E1 - estrone - menopause

E2 - estradiol - nonpregnant females at the right age usually have boyfriends, so woman + man = 2
E3 - estriol - pregnancy - woman + man + baby = 3


Functions 

While estrogens are present in both men and women, they are usually present at significantly higher levels in women of reproductive age.

They promote the development of female secondary sexual characteristics, such as breasts, and are also involved in the thickening of the endometrium and other aspects of regulating the menstrual cycle.

In males, estrogen regulates certain functions of the reproductive system important to the maturation of sperm and may be necessary for a healthy libido. Furthermore, there are several other structural changes induced by estrogen in addition to other functions.


  • Structural
    • promote formation of female secondary sex characteristics
    • reduce muscle mass
    • accelerate metabolism
    • increase fat stores
    • stimulate endometrial growth
    • increase uterine growth
    • increase vaginal lubrication
    • thicken the vaginal wall
    • maintenance of vessel and skin
    • reduce bone resorption, increase bone formation
    • morphic change (endomorphic > mesomorphic > ectomorphic)

  • Protein synthesis
    • increase hepatic production of binding proteins

  • Coagulation
  • Lipid 
    • increase HDL, triglyceride
    • decrease LDL, fat deposition

  • Fluid balance
    • salt (sodium) and water retention
    • increase cortisol, SHBG

  • Gastrointestinal tract
    • reduce bowel motility
    • increase cholesterol in bile

  • Melanin
  • Cancer
    • support hormone-sensitive breast cancer

  • Lung function
    • promotes lung function by supporting alveoli (in rodents but probably in humans).



Reference:
http://www.news-medical.net/health/What-Does-Estrogen-Do.aspx

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From SUPER ENDOCRINOLOGIST

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